The lessons the US can learn from 2009

Moderna is enrolling 30,000 volunteers for its biggest covid-19 vaccine trial

Sponsored by MIT Sloan School of Management The Download Your daily dose of what’s up in emerging technology 07.28.20 Good morning! Today we have a big look at what a green stimulus in the US can do, and an update on the latest vaccine Phase 3 trials. Get your friends to sign up here to get The Download every day. The US needs a green stimulus – but must provide immediate relief first In 2009, amid skyrocketing unemployment and a crippled economy, President Barack Obama signed the $800 billion American Recovery and Reinvestment Act, which included some $90 billion for clean-tech projects and the creation of “green jobs.” Eleven years later, Joe Biden, Obama’s vice president and now the presumptive Democratic nominee for the presidency, has proposed spending $2 trillion on clean energy as a key part of his plan to revive an economy ravaged by the covid-19 pandemic.   Most experts agree that one way or another, it’s going to require massive infusions of government money to prevent a second Great Depression. So why not spend it on one of society’s most critical and intractable challenges: building a sustainable clean-energy infrastructure? The problem is it’s difficult to hit both of those birds—stimulus and climate change—with a single stone.  So it’s worth looking back to the 2009 stimulus bill and asking: What worked? What didn’t? How can we apply those lessons to any future green stimulus? And what can it realistically accomplish? Read the full story. —James Temple Moderna is enrolling 30,000 volunteers for its biggest covid-19 vaccine trial Biotech company Moderna just announced it was working with the US National Institutes of Health to launch what will be one of the largest covid-19 vaccine trials. How does the vaccine work? Moderna’s vaccine works by introducing a viral messenger RNA (mRNA) into the body for human cells to pick up. The human cells use the mRNA to create a fragment of a SARS-CoV-2 viral particle that should not cause an infection, but is enough for the immune system to recognize as a foreign antigen.  How promising is this vaccine? It has shown good results in earlier trials, leading to strong antibody production with tolerable side effects.  The phase 3 trial: The study will enroll up to 30,000 participants, from 89 sites across the US. Researchers want to know not just how well the vaccine prevents infection, but also whether it can limit the severity of the illness when infections still do occur.  What other vaccines are at this stage? According to the New York Times’ vaccine tracker, there are five other vaccines undergoing phase 3 trials—one spearheaded by researchers from the University of Oxford and AstraZeneca (which is testing people from several countries in the largest trial in the world), and three from Chinese groups. Pfizer and a German company called BioNTech are also working on an mRNA vaccine that has just started, also with 30,000 volunteers. —Neel V. Patel We can still have nice things A place for comfort, fun and distraction in these weird times. (Got any ideas? Drop me a line or tweet 'em at me.) + Oooh, light in slow motion. + What is in the Green Banana? + Check out the finalists of this beautiful space photography contest.  The top ten must-reads I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology. 1 Some countries have reopened schools. What did they learn? The age of the children seems to play a factor. (Wired)   + We need the answer to these three questions before we know if it’s safe. (TR) 2 The ransomware attack on Garmin might be the work of Russian cybercriminals Services have been offline for three days—and EvilCorp may be to blame. (Guardian)   + A massive data leak has unused Nintendo prototypes. (Ars Technica) 3 Masks might make the wearer safe too It looks like it reduces viral load. So, y’know, WEAR ONE. (NYT)   + And, no, they don’t violate The Constitution. (The Conversation) 4 The meaningless comfort of covid hygiene theater You can stop washing your grocery shopping now. (Atlantic) 5 Big Tech’s CEOS are preparing for their Big Tobacco moment The four big names will appear before a congressional hearing tomorrow. Don’t expect fireworks. (NYT)   + Googlers aren't going back to the office anytime soon. (WSJ) 6 Maybe it’s ok if countries hack each other’s vaccines? Because one nation shouldn’t own it in the first place. (Vice) 7 How the UK’s NHS coped with the covid-19 onslaught Behind the scenes with the medical staff on the front line. (Economist, 1843)   + Is covid-19 creating a generation of heart failure patients? (The Daily Beastand Stat) 8 Car firms want to monitor your emotions while you drive AI GET OUTTA MY WAY. (Motherboard) 9 Some of TikTok’s biggest influencers are considering their exit strategy Clout is one thing but it doesn’t always translate to $$$. (iNews)   + The chain mail of black and white selfies on Instagram. (NYT) 10 This app lets you see what it’s like to be someone else on Twitter Vicariously.io lets you scroll through Trump’s feed, for example. 😑 (Mashable) Are you intellectually curious? Tech obsessed? We are too. Subscribe to MIT Technology Review today for an insightful and discerning look into the technology for the future without getting bogged down by the jargon. Quote of the Day “You couldn’t trust what he said. You would verify everything that he did and take everything he did with a grain of salt.” Dr Vanessa Olcese talks to The New York Times about her time working with Dr Sapan Desai at Duke University Medical Center. Desai was behind two high-profile studies that were retracted in June. Top image credit: EMILY HAASCH Please send masks to hi@technologyreview.com. Follow me on Twitter at @niallfirth. Thanks for reading! —Niall Was this newsletter forwarded to you, and you'd like to see more? Sign up for free Leading with Innovation. Join us online, October 19-22. You received this newsletter because you subscribed with your email address

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